nucleoside reverse transcriptase inhibitors

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• Discovery and development of non-nucleoside reverse-transcriptase inhibitors — Non nucleoside reverse transcriptase inhibitors (NNRTIs) are antiretroviral drugs used in the treatment of human immunodeficiency virus (HIV). NNRTIs inhibit reverse transcriptase (RT), an enzyme that controls the replication of the genetic… …   Wikipedia

• Nucleoside Reverse Transcriptase Inhibitor — Reverse Transkriptase des HIV 1 Nukleosidische Reverse Transkriptase Inhibitoren (engl. Nucleoside Reverse Transcriptase Inhibitors, NRTI) sind Arzneistoffe aus der Gruppe der Virostatika. Es handelt sich um Nukleosid Analoga, die den natürlichen …   Deutsch Wikipedia

• Discovery and development of nucleoside and nucleotide reverse-transcriptase inhibitors — (NRTIs and NtRTIs) began in the 1980s when the AIDS epidemic hit Western societies. NRTIs inhibit the reverse transcriptase (RT), an enzyme that controls the replication of the genetic material of the human immunodeficiency virus (HIV). The first …   Wikipedia

• Reverse-transcriptase inhibitor — Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors,[1] and cancer.[2] RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce.… …   Wikipedia

• Reverse transcriptase inhibitor — Reverse transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors [ [http://jcem.endojournals.org/cgi/content/full/90/10/5663/F1 Reverse Transcriptase Inhibitors Down Regulate Cell Proliferation in… …   Wikipedia

• reverse transcriptase inhibitor — n an agent that inhibits the activity of a reverse transcriptase esp a drug (as AZT) that acts by inhibiting retroviral reverse transcription * * * a substance that blocks activity of the reverse transcriptase of a retrovirus and is used as an… …   Medical dictionary

• Reverse transcriptase — Protbox Name=Reverse Transcriptase Photo=1HMV.png|250px Caption=3D model of HIV reverse transcriptase HGNCid = Symbol = AltSymbols = Chromosome = Arm = Band = LocusSupplementaryData = Gene= Gene type= Protein length= Molecular weight= Structure=… …   Wikipedia

• Nucleoside analogue — Nucleoside analogues are a range of antiviral products used to prevent viral replication in infected cells. The most commonly used is Acyclovir, although its inclusion in this category is uncertain, as it contains only a partial nucleoside… …   Wikipedia

• Nucleoside analogues — are a range of antiviral products used to prevent viral replication in infected cells. The most commonly used is Aciclovir. FunctionThey work as antimetabolites by being similar enough to nucleosides to be incorporated into growing DNA strands,… …   Wikipedia

• Nukleotidische Reverse-Transkriptase-Inhibitoren — Reverse Transkriptase des HIV 1 Nukleosidische Reverse Transkriptase Inhibitoren (engl. Nucleoside Reverse Transcriptase Inhibitors, NRTI) sind Arzneistoffe aus der Gruppe der Virostatika. Es handelt sich um Nukleosid Analoga, die den natürlichen …   Deutsch Wikipedia

• Discovery and development of HIV-protease inhibitors — Many major physiological processes depend on regulation of proteolytic enzyme activity and there can be dramatic consequences when equilibrium between an enzyme and its substrates is disturbed. In this prospective, the discovery of small molecule …   Wikipedia